Expiration | Code | ||
---|---|---|---|
somatropin, Norditropin, Novo Nordisk Inc. | |||
2114-05-31 | Orphan excl. | ||
somatropin, Humatrope, Eli Lilly and Company | |||
2113-11-01 | Orphan excl. | ||
somatropin, Genotropin, Pharmacia & Upjohn Company LLC | |||
2108-07-25 | Orphan excl. | ||
somatropin, Nutropin, Genentech, Inc. | |||
2103-12-30 | Orphan excl. | ||
somatropin, Serostim, EMD Serono, Inc. | |||
2103-08-23 | Orphan excl. |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Laron syndrome | D046150 | Orphanet_633 | E34.321 | 9 | 23 | 37 | 23 | 35 | 126 |
Turner syndrome | D014424 | Orphanet_881 | Q96 | 1 | 4 | 7 | 6 | 10 | 28 |
Healthy volunteers/patients | — | — | — | 12 | — | — | 3 | 3 | 18 |
Inborn genetic diseases | D030342 | EFO_0000508 | — | 1 | — | 5 | 3 | 8 | 17 |
Infertility | D007246 | HP_0000789 | — | 2 | 4 | 2 | 4 | 2 | 12 |
Hiv infections | D015658 | EFO_0000764 | B20 | 2 | 3 | 3 | 2 | 4 | 12 |
Prader-willi syndrome | D011218 | Orphanet_739 | Q87.11 | 1 | — | 4 | 2 | 4 | 11 |
Chronic renal insufficiency | D051436 | — | N18 | 1 | 1 | 2 | 4 | 2 | 10 |
Hypopituitarism | D007018 | EFO_0001380 | E23.0 | — | 3 | 2 | 3 | 3 | 10 |
Pituitary dwarfism | D004393 | EFO_1001109 | E23.0 | — | 1 | 2 | 3 | 3 | 9 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Growth disorders | D006130 | — | — | 4 | 1 | 7 | — | 4 | 16 |
Noonan syndrome | D009634 | Orphanet_648 | Q87.19 | — | — | 4 | — | 3 | 7 |
Cystic fibrosis | D003550 | EFO_0000390 | E84 | 1 | 3 | 2 | — | 2 | 7 |
Heart failure | D006333 | HP_0001635 | I50 | — | 5 | 2 | — | — | 7 |
Pituitary diseases | D010900 | — | E23.7 | — | — | 4 | — | 1 | 5 |
Endocrine system diseases | D004700 | EFO_0001379 | E34.9 | — | — | 5 | — | — | 5 |
Crohn disease | D003424 | EFO_0000384 | K50 | — | 3 | 1 | — | 1 | 4 |
Dwarfism | D004392 | HP_0003510 | E34.31 | — | 2 | 2 | — | — | 4 |
Cognitive dysfunction | D060825 | HP_0001268 | G31.84 | 1 | 1 | 1 | — | — | 3 |
Osteoporosis | D010024 | HP_0000939 | M81.0 | — | 1 | 1 | — | 1 | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Aging | D000375 | GO_0007568 | R41.81 | 1 | 3 | — | — | 1 | 4 |
Insulin resistance | D007333 | HP_0000855 | E88.819 | 1 | 1 | — | — | 2 | 3 |
Non-alcoholic fatty liver disease | D065626 | EFO_0003095 | K75.81 | 1 | 1 | — | — | — | 2 |
Hiv-associated lipodystrophy syndrome | D039682 | EFO_1001348 | — | 1 | 1 | — | — | 1 | 2 |
Chronic kidney disease-mineral and bone disorder | D012080 | EFO_1001152 | N25.0 | — | 1 | — | — | — | 1 |
Amyotrophic lateral sclerosis | D000690 | HP_0007354 | G12.21 | — | 1 | — | — | — | 1 |
Gonadal dysgenesis | D006059 | — | — | — | 1 | — | — | — | 1 |
Rupture | D012421 | — | — | — | 1 | — | — | — | 1 |
Body weight changes | D001836 | — | — | 1 | 1 | — | — | — | 1 |
Tendinopathy | D052256 | EFO_1001434 | M77.9 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Facioscapulohumeral muscular dystrophy | D020391 | EFO_0000491 | G71.02 | 1 | — | — | — | — | 1 |
Knee osteoarthritis | D020370 | EFO_0004616 | M17 | 1 | — | — | — | — | 1 |
Hypophosphatemic rickets | D063730 | — | E83.31 | 1 | — | — | — | — | 1 |
Post-concussion syndrome | D038223 | EFO_1001827 | F07.81 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Metabolic diseases | D008659 | EFO_0000589 | E88.9 | — | — | — | — | 3 | 3 |
Acromegaly | D000172 | — | — | — | — | — | — | 2 | 2 |
Fatty liver | D005234 | EFO_0003934 | — | — | — | — | — | 1 | 1 |
Metabolism | D008660 | GO_0008152 | — | — | — | — | — | 1 | 1 |
Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | — | — | — | — | 1 | 1 |
Ketosis | D007662 | HP_0002919 | R82.4 | — | — | — | — | 1 | 1 |
Polycystic ovary syndrome | D011085 | EFO_0000660 | E28.2 | — | — | — | — | 1 | 1 |
Pituitary neoplasms | D010911 | — | — | — | — | — | — | 1 | 1 |
Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | — | — | — | — | 1 | 1 |
Werner syndrome | D014898 | Orphanet_902 | E34.8 | — | — | — | — | 1 | 1 |
Drug common name | Somatropin pegol |
INN | somatropin pegol |
Description | Genotropin, Humatrope, Norditropin, Nutropin, NutropinAq, Omnitrope, Serostim, Zomacton (somatropin pegol) is a protein pharmaceutical. Somatropin pegol was first approved as Humatrope on 1986-10-16. It has been approved in Europe to treat growth, pituitary dwarfism, prader-willi syndrome, and turner syndrome. |
Classification | Protein |
Drug class | PEGylated compounds, covalent attachment of macrogol (polyethylene glycol) polymer; tricyclic compounds; growth hormone derivatives; atropine derivatives |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | — |
PDB | — |
CAS-ID | — |
RxCUI | — |
ChEMBL ID | CHEMBL2108315 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | — |
UNII ID | ZF7544FTQW (ChemIDplus, GSRS) |